PGT-A with ploidy

• To enhance the genetic testing of IVF embryos and expand the diagnostic capabilities and clinical utility of our preimplantation genetic testing for aneuploidy (PGT-A), we have developed and validated a parallel targeted Next-Generation Sequencing (NGS) strategy using the power of SNP technology without the need for parental samples.

• Single Nucleotide Polymorphisms (SNPs) are changes in single nucleotides distributed throughout the genome which frequently vary at the same genomic position between individuals. Most SNPs have only two different alleles.
• SNPs can be used to detect ploidy differences.

• This dual assessment serves as a complementary test for the detection of the chromosome abnormalities not detected with our current approach, significantly enhancing the accuracy and confidence of the PGT-A test.

What is PGT-A with ploidy?

• Building upon our expertise, our latest offering, PGT-A with ploidy detection, is a 2-in-1 genetic test which combines our extensively validated in-house Next Generation Sequencing (NGS) technology with an additional and validated targeted Next Generation Sequencing (NGS) strategy using the power of SNPs (Single Nucleotide Polymorphism) without the need for parental samples.
• This advanced screening solution goes beyond PGT-A by incorporating additional features including ploidy analysis (complete chromosomes sets) into a standard PGT-A workflow significantly increasing accuracy and confidence in selecting the optimal embryo for transfer.

PGT-A with ploidy

Our most advanced 2-in-1 genetic test solution

PGT – A

Our custom and validated technology that combines next-generation sequencing (NGS) with advanced algorithms and machine learning, enabling the analysis of genomic data from embryos with exceptional accuracy and reliability.

Genetic PN Check | Ploidy detection

PGT-A with ploidy enables the detection of both haploidy and triploidy. This crucial assessment ensures the selection of embryos with the correct chromosomal content, minimizing the risk of genetic abnormalities. PGT-A with ploidy also increases the number of viable euploid embryos available for transfer by detecting true 2PN (diploid) embryos from among morphologically identified 0, 1 and 2.1/3PN embryos.