CGT: Carrier Genetic Test

Who should use CGT test?

• Couples who plan on forming a family and want to know the risk of transmitting hereditary disorders to their children
• Patients planning an assisted reproduction treatment
• Patients planning a treatment with donor sperm or eggs

Most carriers of genetic mutations don’t have a family history of these disorders.

Why use CGT test?

Is a clinically validated genetic screening test based on Next-Generation Sequencing (NGS).
Our different CGT options, tailored to each patient’s needs, make it the most complete test available.

Test limitations

• The sensitivity of the test is 98%.
• We only analyse genes on the list available here, reporting results based on knowledge current at the time of testing. Therefore, only genes included in this list will be detected.
• The method is based on analysis by massive parallel sequencing and bioinformatics, studying all the exons of the genes included on our gene list. This includes adjacent intronic regions before or after position +5 and -5. Variants located outside the gene regions studied, such as gene-expression regulatory regions or intronic regions before or after position +5 and -5 are not detected.
• No inversions, deletions, or duplications over 20 nucleotides long that are not referred to in the list available here are studied.
• Germ mosaics (mutations only present in gametes) are not detected by this analysis because the DNA material studied is obtained from a blood sample.
• A negative result for the genes indicated does not exclude the possibility that a de novo mutation may appear in the offspring.